The focus view will let you work efficiently on one namespace in one language. The view is divided into three columns:
Left Column: A list of all your keys/segments in that file. Can be searched and filtered.
Center Column: Editing of the currently selected key/segment
Right Column: Extended Translation functions like Translation Memory, Machine Translation access, History of changes, values in other languages, context information, character max length settings, etc...
This view is the primary view for translators working focused on translating the content.
Using keybindings to jump between segments and save you should be able to work using mostly your keyboard.